Destruction of the Ranch
The Ranch is destroyed in the mission Crystal Maze. During that mission, the O'Neils steal a drug contract from Trevor. An angry Trevor, controlled by the player, kills all but three of the O'Neils. Trevor then pours a gas trail from the basement to the outside of the house. He then fires at the gas trail left by him and drives away on an ATV. The house eventually explodes and proceeds to burn down completely.
After Crystal Maze
If the player chooses to return to the area, the house is in ruins and the fire has been extinguished. Except for the basement, the house is still accessible. Nearby, a random event will trigger, in which a police officer chases down a criminal, and they will commonly pass through the house. There is also a parachute mission nearby. More speculative myth hunters have put forth theories that the house may be haunted, supported either by the old architecture, or that Trevor himself caused the haunting by killing people in the area. These claims are backed up with strange sounds heard at night.
- In GTA Online, the player can play at the O'Neil Ranch during the Every Bullet Counts freemode event.