Marvin Trill mentions the arcade game during an episode of Area 53, claiming the game puts subliminal messages in player's heads.
I hear what you’re saying about video games. People are dying every day of Malaria and it’s all because of the messages planted in our minds from that Degenertron in the 80s.
A strange man on Vice City radio also claims to empty machines each week. It has been described that Degenatron is based on the real-life Polybius urban legend which stated that the game was part of a government-run crowdsourced psychology experiment, with gameplay producing intense psychoactive and addictive effects in the player. These few publicly staged arcade machines were said to have been visited periodically by men in black for the purpose of data-mining the machines and analyzing these effects.