This pedestrian is based on Sharon Stone's character from the 1992 movie Basic Instinct. In the movie, the woman, named Catherine Tramell, is a serial killer, who kills her partner after sex with an ice pick. The SFPD (San Francisco Police Department) dubs the unnamed murderer the Ice Pick Killer. The woman is usually the prime suspect, but she seduces the cops and always gets off. Then a detective (Michael Douglas) is put on the case and ends up finding the murder weapon and eventually links her to the murders.
In GTA San Andreas, the woman can be found in the Los Santos jail and around the city as well, as in San Fierro, where the movie is based in, thus marking this as an Easter egg.